Cart
sales@molnova.com
AG 126
CAS No. 118409-62-4
AG 126 ( AG 126; Tyrphostin AG 126; UNII-7YA4AMD1JC )
Catalog No. M17173 CAS No. 118409-62-4
The tyrphostin AG-126 selectively inhibits the phosphorylation of ERK1 (p44) and ERK2 (p42) at 25-50 μM.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 39 | In Stock |
|
| 5MG | 60 | In Stock |
|
| 10MG | 105 | In Stock |
|
| 25MG | 210 | In Stock |
|
| 50MG | 311 | In Stock |
|
| 100MG | 462 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameAG 126
-
NoteResearch use only, not for human use.
-
Brief DescriptionThe tyrphostin AG-126 selectively inhibits the phosphorylation of ERK1 (p44) and ERK2 (p42) at 25-50 μM.
-
DescriptionAG 126 selectively inhibits the phosphorylation. It also acts as a cell-permeable inhibitor of lipopolysaccharide (LPS)-induced synthesis of tumor necrosis factor-α and nitric oxide in murine peritoneal macrophages.
-
SynonymsAG 126; Tyrphostin AG 126; UNII-7YA4AMD1JC
-
PathwayCytoskeleton/Cell Adhesion Molecules
-
TargetAkt
-
RecptorCOX-2; ERK1,2
-
Research AreaInflammation/Immunology
-
Indication——
Chemical Information
-
CAS Number118409-62-4
-
Formula Weight215.17
-
Molecular FormulaC10H5N3O3
-
Purity98%
-
SolubilityDMSO : 100 mg/mL. 464.75 mM;
-
SMILESC1=CC(=C(C=C1C=C(C#N)C#N)O)[N+](=O)[O-]
-
Chemical NamePropanedinitrile, ((3-hydroxy-4-nitrophenyl)methylene)-
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Novogrodsky, A.,Vanichkin, A.,Patya, M., et al. Prevention of lipopolysaccharide-induced lethal toxicity by tyrosine kinase inhibitors. Science 264(5163), 1319-1322 (1994).
molnova catalog
related products
-
10-NCP
10-NCP (10-DEBC) is a potent neuronal autophagy inducer and increases TDP43 clearance, a reversible and specific inhibitor of Akt activity in vitro.
-
CCT128930
CCT128930 is a potent, selective, ATP-competitive AKT inhibitor with IC50 of 6 nM (AKT2).
-
Marein
Marein shows neuroprotective effect on PC12 cell damage induced by methylglyoxal, which is due to a reduction of damage to mitochondria function and activation of the AMPK signal pathway.
