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AG 126
CAS No. 118409-62-4
AG 126 ( AG 126; Tyrphostin AG 126; UNII-7YA4AMD1JC )
Catalog No. M17173 CAS No. 118409-62-4
The tyrphostin AG-126 selectively inhibits the phosphorylation of ERK1 (p44) and ERK2 (p42) at 25-50 μM.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 39 | In Stock |
|
| 5MG | 60 | In Stock |
|
| 10MG | 105 | In Stock |
|
| 25MG | 210 | In Stock |
|
| 50MG | 311 | In Stock |
|
| 100MG | 462 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAG 126
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NoteResearch use only, not for human use.
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Brief DescriptionThe tyrphostin AG-126 selectively inhibits the phosphorylation of ERK1 (p44) and ERK2 (p42) at 25-50 μM.
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DescriptionAG 126 selectively inhibits the phosphorylation. It also acts as a cell-permeable inhibitor of lipopolysaccharide (LPS)-induced synthesis of tumor necrosis factor-α and nitric oxide in murine peritoneal macrophages.
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SynonymsAG 126; Tyrphostin AG 126; UNII-7YA4AMD1JC
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetAkt
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RecptorCOX-2; ERK1,2
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Research AreaInflammation/Immunology
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Indication——
Chemical Information
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CAS Number118409-62-4
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Formula Weight215.17
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Molecular FormulaC10H5N3O3
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Purity98%
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SolubilityDMSO : 100 mg/mL. 464.75 mM;
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SMILESC1=CC(=C(C=C1C=C(C#N)C#N)O)[N+](=O)[O-]
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Chemical NamePropanedinitrile, ((3-hydroxy-4-nitrophenyl)methylene)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Novogrodsky, A.,Vanichkin, A.,Patya, M., et al. Prevention of lipopolysaccharide-induced lethal toxicity by tyrosine kinase inhibitors. Science 264(5163), 1319-1322 (1994).
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